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Glyphosate Exposure Linked to Long-Term Brain Inflammation

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06 Dec, 2024

This post was originally published on Eco Watch

A new study led by Arizona State University has revealed an association between exposure of glyphosate, one of the most commonly used herbicides in the world, and long-term impacts on brain health in mice.

The study tested the impacts that two different doses of glyphosate exposure had on mice, with a high dose (500 mg per kg) and a lower dose (50 mg per kg), which was similar to the amount that was used to determine the acceptable dose of exposure to humans. The researchers observed how the exposure impacted the brains during a 13-week exposure as well as six months after exposure had ended compared to the control mice, which received no glyphosate exposure.

The team determined that glyphosate exposure led to neuroinflammation as well as behaviors and symptoms similar to anxiety and Alzheimer’s. For some of the animals, the exposure was associated with results as extreme as premature death.

Even the low dose led to negative impacts on the brains that lasted several months after exposure had ended. The scientists published their findings in the journal Journal of Neuroinflammation.

“My hope is that our work drives further investigation into the effects of glyphosate exposure, which may lead to a reexamination of its long-term safety and perhaps spark discussion about other prevalent toxins in our environment that may affect the brain,” Samantha Bartholomew, first author of the paper and a Ph.D. candidate at Arizona State University, said in a statement.

A farmer sprays glyphosate on an apple orchard in Asperen, the Netherlands on March 31, 2019.
Hans Verburg / iStock Editorial / Getty Images Plus

These results have raised concerns over the current standards for glyphosate, which is considered to have no concerning risks to human health when used as directed on the label, according to the U.S. Environmental Protection Agency. 

Further, the researchers warned about the potential impacts to aging populations, which are already experiencing an increase in cognitive decline, according to Ramon Velazquez, a co-author of the study, researcher with the ASU-Banner Neurodegenerative Disease Research Center and assistant professor of life sciences.

But the researchers hope that more investigation is completed to determine if the current acceptable limits of glyphosate are too high, or whether any exposure of glyphosate poses risks.

“Herbicides are used heavily and ubiquitously around the world,” said Patrick Pirrotte, senior author of the study and associate professor at the Early Detection and Prevention Division at Translational Genomics Research Institute (TGen). “These findings highlight that many chemicals we regularly encounter, previously considered safe, may pose potential health risks. However, further research is needed to fully assess the public health impact and identify safer alternatives.”

While the findings brought up the question of what these impacts observed on brains of mice could mean for glyphosate exposure and its potential impacts on human brains, it can also be used as an example to further research alternatives to testing on mice and other animals. Because of the complexity of brains, it is currently still common to use animal testing to observe reactions and impacts in brain research. 

As Cruelty-free International reported, researchers are working on other ways to complete these important types of organ and nervous system studies without the use of animal testing. Scientists are rapidly exploring and advancing alternatives, such as computer modeling, tissue donations, cell cultures and “human-on-a-chip” models for brain research. PETA reported that AI is becoming more suitable as a method for alternative testing. However, more research on non-animal testing is necessary, and once alternatives are more established, they will require regulation to be implemented.

The post Glyphosate Exposure Linked to Long-Term Brain Inflammation appeared first on EcoWatch.

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Embedding environmental stewardship into IT governance frameworks

Embedding environmental stewardship into IT governance frameworks

Integrating environmental stewardship into IT governance frameworks has become essential as businesses increasingly prioritise sustainability. IT operations contribute significantly to carbon emissions, energy consumption and electronic waste (e-waste). Organisations that embed environmental responsibility into their IT governance can reduce their ecological footprint, improve operational efficiency and strengthen their brand reputation.

Erica Smith, chief alliance officer and environmental, social and governance lead, Blue Connections IT, said, “Environmental stewardship supports financial performance, risk mitigation and brand differentiation. With rising energy costs, increased consumer demand for sustainable products and services, and growing pressure from investors and regulators, companies can no longer afford to overlook their environmental responsibilities.

“Poor sustainability practices in IT can lead to high operational costs, supply chain risks and reputational damage. Conversely, a proactive approach improves efficiency, attracts environmentally conscious customers and helps future-proof businesses against evolving policy and regulatory changes.

“Integrating environmental responsibility into IT governance integrates sustainability initiatives into decision-making systematically. Organisations can reduce waste, lower energy consumption and extend the lifecycle of technology assets while positioning themselves as responsible leaders in an increasingly climate-aware market.”

There are four key areas that present opportunities to embed environmental stewardship into IT governance frameworks.

1. Device lifecycle management

A structured approach to managing the lifecycle of IT assets ensures devices are deployed efficiently, maintained properly and retired responsibly at the end of their useful life. Embracing a circular economy model, where equipment is refurbished, reused or ethically recycled, can significantly reduce e-waste and resource use. Companies that adopt this approach lower their environmental impact and unlock financial value by extending the lifecycle of IT assets.

Smith said, “Effective asset recovery strategies further support sustainability efforts. Integrating secure data erasure and refurbishment into IT governance policies lets businesses repurpose functional devices within the organisation or resell them to external buyers. Responsible e-waste recycling also supports companies to process materials ethically in instances where resale is not viable, reducing landfill contributions and preventing environmental contamination. The adoption of industry-certified data sanitisation methods also safeguards compliance with security and privacy regulations.”

2. Sustainable procurement

IT governance frameworks should prioritise the selection of technology vendors and partners committed to sustainable manufacturing, responsible sourcing and energy-efficient product design. This includes favouring IT hardware with a high percentage of post-consumer recycled materials and using minimal packaging. Additionally, employing Device-as-a-Service (DaaS) models optimises IT asset utilisation while reducing upfront investment and unnecessary hardware purchases.

Partnerships with sustainability-driven IT service providers can further enhance an organisation’s environmental impact. Working with partners that offer end-to-end IT asset management solutions, encompassing secure device deployment, certified data sanitisation and ethical recycling, simplifies the process of aligning IT operations with sustainability goals. Companies that prioritise environmental stewardship in their IT governance framework gain a competitive advantage by demonstrating their commitment to responsible business practices.

3. Energy consumption

Data centres, cloud services and enterprise networks require substantial energy resources, making green IT practices essential. IT governance frameworks should include policies to reduce consumption by optimising server efficiency, reducing redundant infrastructure and using renewable energy sources. Cloud providers with strong sustainability credentials can support carbon reduction initiatives, while virtualisation strategies can consolidate workloads and improve overall energy efficiency.

4. Employee engagement

Educating staff on sustainable IT practices, such as energy-efficient device usage and responsible e-waste disposal, creates a culture of accountability. Organisations that implement green workplace initiatives, such as responsible end-of-life disposal programs, reinforce their commitment to sustainability at all levels.

“IT governance must also align with corporate environmental, social and governance commitments. Companies can contribute to broader sustainability objectives by embedding environmental stewardship into IT policies, such as net-zero emissions targets and responsible supply chain management. Clear reporting mechanisms and regular sustainability audits aid transparency, letting businesses track their progress and demonstrate accountability to stakeholders,” Smith said.

Government regulations and evolving industry standards are increasingly shaping the sustainability expectations for organisations. Aligning IT governance frameworks with best practices for environmental stewardship keeps companies ahead of regulatory requirements. Proactive adoption of sustainable IT practices positions businesses as industry leaders in environmental responsibility.

Smith said, “Integrating environmental stewardship into IT governance frameworks is not just about meeting compliance obligations; it’s about futureproofing company operations and prioritising the broader environment. Taking a proactive approach to sustainability lets organisations drive efficiency, reduce long-term costs and contribute to a healthier planet. Businesses that lead in sustainable IT governance will be well-positioned for long-term success as environmental concerns continue to shape consumer and corporate priorities.”

Image credit: iStock.com/Petmal

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